It’s almost perfect. A supplement that can increase focus, sharpen memory, and even enhances athletic ability.
Recent studies have found that Alpha GPC might really be the most comprehensive performance enhancer currently available.
Alpha GPC (alpha glycerylphosphoryl choline), is a molecule that functions as a ready source of choline; an essential nutrient.
Alpha GPC is a natural compound found in the healthy brain (1). It’s used in supplements for both improved cognitive function and increased muscle strength.
Alpha GPC, also called choline alfoscerate, delivers choline to the brain and helps your body produce the critical neurotransmitter acetylcholine, which is what produces its many benefits.
Although acetylcholine is strongly involved in memory and learning, it’s also one of the most important neurotransmitters for powerful muscle contractions.
Levels of acetylcholine can naturally decline with age (2). To ensure you have enough of this brain chemical to function at your best, you need to keep levels up.
People with low acetylcholine levels can experience muscle weakness and significant cognitive problems (2).
Alpha GPC easily crosses the blood-brain-barrier, unlike other popular choline supplements on the market (3).
This is why it’s attracted the attention of athletes, students, and people in professions where peak mental performance is essential.
It’s so effective that the medical community is using it for the treatment of memory disorders like Alzheimer’s disease (4).
Choline in its basic form is usually found as bitartrate. This is the most common choline supplement, and while it can benefit the body it won’t reliably increase choline in the brain.
This makes it ineffective for cognitive enhancement (3). Something also true for another simple choline called choline citrate (3).
However, Alpha GPC is 40 percent choline by weight (5), and is actually a prodrug that’s metabolized by the body to make both choline and glycerophosphate, which helps maintain cell health (5).
So far, Alpha GPC is the most efficient form of choline supplementation because unlike other choline supplements, it’s:
Alpha GPC improves memory, learning and thinking ability by increasing acetylcholine levels in the brain.
In a placebo-controlled trial published in Clinical Therapeutics the effectiveness and tolerability of Alpha GPC was assessed in the treatment of cognitive impairment due to mild-to-moderate Alzheimer’s disease (6).
In the Alpha GPC group, cognition, behavior, and mental state consistently improved after three and six months of treatment. The placebo group remained unchanged or got worse.
But what about healthy people who take Alpha GPC?
A cohort study involving healthy participants found that higher choline intake was linked with much better mental performance.
The cognitive abilities assessed included verbal memory, visual memory, verbal learning, and executive function. (7)
A 2015 study compared Alpha GPC to caffeine with participants in their twenties who all took the same math test to test the effects each substance had on mental performance.
Test were accurately completed almost 20 percent faster in subjects who received 400 milligrams of Alpha GPC compared to those who took 200 milligrams of caffeine. The group using caffeine also reported significantly more nervousness compared to the Alpha GPC group. (8)
Short supplementation periods of six days have directly improved muscle strength in college-aged athletes.
A study conducted at the University of Louisiana used an isometric strength test to measure the force generated in deadlift and bench press style movements (9).
The study found a significant increase in lower body strength with Alpha GPC supplementation. The researchers concluded that it was effective at increasing lower body force production after just six days of use. They added that sport performance coaches should consider adding it to the diet of speed and power athletes to enhance performance (9).
An increase in circulating choline levels also increases growth hormone levels.
A Japanese study examined the effect of a single dose of Alpha GCP on growth hormone secretion in healthy young males (10).
They found that one dose caused a substantial increase in growth hormone secretion after only one hour. Growth hormone levels rose by almost 300 percent from baseline hormone levels.
Researchers also detected a rise in free fatty acids and ketone bodies that indicate accelerated fat burning metabolism (10). They believe it’s the increase in circulating choline that blocks the negative feedback mechanism that governs normal GH release.
Next Level Superfoods Multivitamin includes 300 mg of Alpha-GPC in it’s formulation.
We also include:
As part of our Mental Energy, Clarity and Focus Support!
REFERENCES
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Rhodiola Rosea stands out as a potent adaptogenic herb with a rich history of traditional use and a growing body of scientific research. Revered for
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